Disodium Guanylate

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Definition

Disodium guanylate is a food additive that is commonly used as a flavor enhancer. Typically used in combination with monosodium glutamate (MSG) to enhance the savory or umami flavor of foods. It is particularly effective in enhancing the flavor of meats, soups, and sauces.

Also Known As

sodium 5'-guanylate, disodium 5'-guanylate, E627

Health Impact

Adverse reactions such as headaches, skin rash, or gastrointestinal symptoms may occur. Since it is ofter paired with MSG, those sensitive to MSG should avoid it. People with gout or a history of uric acid kidney stones should also avoid disodium guanylate because guanylates often metabolize to purines, which are compounds that can raise uric acid levels in your body.

Sources