Artificial sweetener made of aspartic acid and phenylalanine. It is 200 times sweeter than sugar and widely used in packaged foods, particularly "diet" drinks, gums, and foods.
Aspartame can harm the gut and negatively impact gluten tolerance and metabolism. Has been shown to cause cancer in studies done on mice and linked to risk of lymphoma and leukemia in men and women. Consumption is also linked to increased risk of heart disease. Aspartame has carcinogenic potential, may alter cell viability, alter brain antioxidant status, and can promote hyperglycemia. Also has been shown to cause headaches.
Artificial sweeteners and cancer risk: Results from the NutriNet-Santé population-based cohort studyhttps://journals.plos.org/plosmedicine/article?id=10.1371/journal.pmed.1003950
Aspartame—True or False? Narrative Review of Safety Analysis of General Use in Productshttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC8227014/
Chemical Cuisine - Safety of food additiveshttps://cspinet.org/eating-healthy/chemical-cuisine#carbosodium
Aspartame administered in feed, beginning prenatally through life span, induces cancers of the liver and lung in male Swiss micehttps://pubmed.ncbi.nlm.nih.gov/20886530/
Identification of aspartame-induced haematopoietic and lymphoid tumours in rats after lifetime treatmenthttps://pubmed.ncbi.nlm.nih.gov/32622430/
Consumption of artificial sweetener– and sugar-containing soda and risk of lymphoma and leukemia in men and womenhttps://cspinet.org/resource/consumption-artificial-sweetener-and-sugar-containing-soda-and-risk-lymphoma-and-leukemia
Artificial sweeteners and risk of cardiovascular diseases: results from the prospective NutriNet-Santé cohorthttps://www.bmj.com/content/378/bmj-2022-071204